In my opinion (and my experience) there is no difference.
Archived discussion
Handle_ vs. Handle() ???
what is difference Handle_ with Handle()?
ex) Handle_Geom_BSplineSurface vs. Handle(Geom_BSplineSurface)
Discussion
2 archived replies
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it is the same.
check the file Standard_Macro.hxx you will find :
#define Handle(ClassName) Handle_##ClassName
HTH,
Commenter-2
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